Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27717302 | 1.00 | TSHR (0.34) | TSHRSLC1A1MEN1KMT2ACA12 | |
| SCHEMBL5129987 | 0.80 | — | — | |
| SCHEMBL27918829 | 0.79 | SLC1A1 (0.41) | TSHRSLC1A1MEN1KMT2ACA12 | |
| SCHEMBL27697420 | 0.79 | SLC1A1 (0.41) | TSHRSLC1A1MEN1KMT2ACA12 | |
| SCHEMBL10806404 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL6399701 | 0.74 | — | — | |
| SCHEMBL5489184 | 0.73 | — | — | |
| SCHEMBL8861989 | 0.72 | CA12 (0.41) | TSHRSLC1A1MEN1KMT2ACA12 | |
| SCHEMBL4730804 | 0.70 | SMN1; SMN2 (0.37) | TSHRMEN1KMT2A | |
| SCHEMBL1649228 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087066-A | Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith | PHARMACOPEIA DRUG DISCOVERY | 2013-05-08 | — | — | CN | disclosed |