Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE2 | Q9Y5Z0 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568403 | 1.00 | BACE2 (0.61) | BACE2 | |
| SCHEMBL620195 | 0.83 | BACE2 (0.64) | BACE2 | |
| SCHEMBL568407 | 0.83 | BACE2 (0.71) | BACE2 | |
| SCHEMBL568408 | 0.83 | BACE2 (0.71) | BACE2 | |
| SCHEMBL568767 | 0.83 | BACE2 (0.63) | BACE2 | |
| SCHEMBL28802304 | 0.83 | BACE2 (0.63) | BACE2 | |
| SCHEMBL568805 | 0.82 | BACE2 (0.65) | BACE2 | |
| SCHEMBL568871 | 0.82 | BACE2 (0.84) | BACE2 | |
| SCHEMBL568872 | 0.82 | BACE2 (0.84) | BACE2 | |
| SCHEMBL568582 | 0.82 | BACE2 (0.67) | BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068806-A | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | SIENA BIOTECH SPA | 2013-04-24 | — | — | CN | claimed |
| CN-103068806-A | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | SIENA BIOTECH SPA | 2013-04-24 | — | — | CN | disclosed |