Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851940 | 0.80 | CYP2C19 (0.43) | CYP2C19ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL568560 | 0.79 | PTPRC (0.44) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL568559 | 0.79 | PTPRC (0.44) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL568561 | 0.79 | PTPRC (0.44) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL27868923 | 0.78 | MEN1 (0.45) | PTPRCALOX5ALDH1A1MAPTMEN1 | |
| SCHEMBL569162 | 0.78 | PTPRC (0.50) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL569163 | 0.78 | PTPRC (0.50) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL7664781 | 0.77 | PTPRC (0.55) | PTPRCALOX5CYP2C19ALDH1A1MAPT | |
| SCHEMBL27901490 | 0.76 | PTPRC (0.43) | PTPRCALOX5ALDH1A1MAPTMEN1 | |
| SCHEMBL3577016 | 0.75 | PTPRC (0.52) | PTPRCALOX5CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068806-A | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | SIENA BIOTECH SPA | 2013-04-24 | — | — | CN | disclosed |