Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 10/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901834 | 0.90 | PROKR1 (0.39) | CNR2PROKR1DPP4DPP9 | |
| SCHEMBL2791389 | 0.89 | CNR2 (0.40) | CNR2PROKR1HRH3PADI4PTGER4 | |
| SCHEMBL7902499 | 0.87 | PROKR1 (0.37) | CNR2PROKR1PADI4DPP4DPP9 | |
| SCHEMBL2792434 | 0.87 | PROKR1 (0.40) | CNR2PROKR1PADI4DPP4DPP9 | |
| SCHEMBL7892716 | 0.87 | PROKR1 (0.39) | CNR2PROKR1DPP4DPP9 | |
| SCHEMBL7897490 | 0.86 | PADI4 (0.41) | CNR2PROKR1PADI4PTGER4 | |
| SCHEMBL2790135 | 0.86 | PROKR1 (0.40) | CNR2PROKR1DPP4DPP9 | |
| SCHEMBL2789838 | 0.86 | PROKR1 (0.37) | CNR2PROKR1DPP4DPP9 | |
| SCHEMBL7900932 | 0.86 | PROKR1 (0.40) | CNR2PROKR1DPP4DPP9 | |
| SCHEMBL7904628 | 0.86 | PROKR1 (0.40) | CNR2PROKR1DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |