Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.46 |
| ▸ | MC5R | P33032 | 3/20 | 0.46 |
| ▸ | MC3R | P41968 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 3/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903274 | 1.00 | MC4R (0.46) | MC4RMC5RMC3RMMP2ALPI | |
| SCHEMBL27920890 | 0.92 | MC4R (0.52) | MC4RMC5RMC3RMMP2ALPI | |
| SCHEMBL27920888 | 0.92 | MC4R (0.52) | MC4RMC5RMC3RMMP2ALPI | |
| SCHEMBL27920904 | 0.92 | MC4R (0.52) | MC4RMC5RMC3RMMP2ALPI | |
| SCHEMBL29221573 | 0.91 | MC4R (0.47) | MC4RMC5RMC3RMMP2ALPI | |
| SCHEMBL28916818 | 0.85 | ALPI (0.44) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL26923164 | 0.85 | MC4R (0.48) | MC4RMC5RMC3RMMP2ALPI | |
| Acetic Acid SCHEMBL25216566 | 0.84 | GSR (0.46) | SLC7A5RNPEPCPB2SLC1A2SLC1A1 | |
| SCHEMBL4271001 | 0.84 | GSR (0.49) | SLC7A5RNPEPCPB2SLC1A2SLC1A1 | |
| SCHEMBL29014900 | 0.84 | SLC7A5 (0.45) | MC4RMC5RMC3RSLC7A5ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749665-B | Conjugates of CC-1065 analogs and bifunctional linkers | 辛塔佳有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-106967062-A | The analogs of novel C C 1065 and its conjugate | 辛塔佳股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-103118679-B | Conjugates of CC-1065 Analogs and Bifunctional Linkers | SYNTARGA B.V. (NL) | 2016-12-14 | — | — | CN | disclosed |
| CN-103118679-A | Novel conjugates of CC-1065 analogs and bifunctional linkers | SYNTARGA BV | 2013-05-22 | — | — | CN | disclosed |