Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FSHR | P23945 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934934 | 0.89 | GSK3B (0.40) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL611654 | 0.89 | GSK3B (0.40) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL19053692 | 0.87 | MAPKAPK2 (0.42) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL13323075 | 0.84 | GSK3B (0.41) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL16679411 | 0.84 | MAPKAPK2 (0.40) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL7452419 | 0.83 | MAPKAPK2 (0.42) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL27886524 | 0.83 | MAPKAPK2 (0.40) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL2668927 | 0.83 | GSK3B (0.40) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL16680405 | 0.83 | MAPKAPK2 (0.41) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B | |
| SCHEMBL16680780 | 0.83 | MAPKAPK2 (0.39) | MAPKAPK2GSK3BDYRK1ANAMPTGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102863396-A | Chemical synthesis method for N-Boc-5-aminopyrazine-2-formaldehyde | UNIV NANTONG | 2013-01-09 | — | — | CN | disclosed |