SCHEMBL27904321

SCHEMBL27904321

O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccncc1Cl

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRACR2A Q9BSW2 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1668209 0.90 CRACR2A (1.00) CRACR2A
SCHEMBL1668019 0.89 CRACR2A (0.81) CRACR2A
Hydrochloric Acid SCHEMBL1887962 0.88 CRACR2A (0.80) CRACR2A
SCHEMBL27904347 0.88 CRACR2A (0.81) CRACR2A
SCHEMBL1668237 0.88 CRACR2A (0.78) CRACR2A
SCHEMBL28073514 0.86 CRACR2A (0.76) CRACR2A
SCHEMBL1668340 0.86 CRACR2A (1.00) CRACR2A
Hydrochloric Acid SCHEMBL1667951 0.85 CRACR2A (0.98) CRACR2A
SCHEMBL27904313 0.85 CRACR2A (0.85) CRACR2A
SCHEMBL1668360 0.84 CRACR2A (1.00) CRACR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102834382-A Pyrazole derivatives as modulators of calcium release-activated calcium channel RHIZEN PHARMACEUTICALS S A 2012-12-19 CN claimed
CN-102834382-A Pyrazole derivatives as modulators of calcium release-activated calcium channel RHIZEN PHARMACEUTICALS S A 2012-12-19 CN disclosed