Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27674642 | 0.87 | ELANE (0.53) | — | |
| Tert-Butyl Formate SCHEMBL27905556 | 0.80 | DEGS1 (0.58) | HDAC3HDAC11HDAC8HDAC6DEGS1 | |
| SCHEMBL27694104 | 0.80 | MAPT (0.57) | — | |
| SCHEMBL27694107 | 0.80 | MAPT (0.57) | — | |
| SCHEMBL9409455 | 0.79 | HDAC3 (0.50) | HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL28778499 | 0.78 | HDAC3 (0.61) | HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL28778473 | 0.78 | HDAC3 (0.61) | HDAC3HDAC11HDAC8HDAC6DEGS1 | |
| SCHEMBL1990859 | 0.78 | HDAC3 (0.61) | HDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL6920605 | 0.78 | — | — | |
| SCHEMBL18553776 | 0.78 | P2RY14 (0.66) | HDAC3HDAC11HDAC8HDAC6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035777-B | HCV replication modulators | ANGELETTI P IST RICHERCHE BIO | 2013-01-02 | — | — | CN | disclosed |