Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663745 | 0.84 | NPC1 (0.58) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL569471 | 0.83 | RET (0.44) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL7932771 | 0.76 | MEN1 (0.55) | MAPTPOLBMEN1KMT2ARET | |
| SCHEMBL18642800 | 0.73 | RET (0.67) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL570055 | 0.72 | MAPT (1.00) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL25474826 | 0.71 | MAPT (0.49) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL18642908 | 0.71 | RET (0.68) | MAPTPOLBMEN1KMT2ARET | |
| SCHEMBL6562826 | 0.71 | NPC1 (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL12038438 | 0.70 | PDPK1 (0.58) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL10133313 | 0.70 | PDPK1 (0.54) | MAPTPOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103154018-B | For passing through the antibody of affinity chromatography and the part of Fc-fusion protein purification | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2016-04-27 | — | — | CN | disclosed |
| CN-103154018-A | Ligands for antibody and Fc-fusion protein purification by affinity chromatography | GRAFFINITY PHARMACEUTICALS GMBH | 2013-06-12 | — | — | CN | disclosed |