Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625542 | 0.80 | MAPK14 (0.47) | PIP5K1CPIK3CAMAPK14PIK3C3MAPK8 | |
| SCHEMBL952377 | 0.80 | MAPK14 (0.48) | PIP5K1CPIK3CAMAPK14PIK3C3MAPK8 | |
| SCHEMBL954285 | 0.77 | PIK3C3 (0.49) | PIP5K1CPIK3CAMAPK14PIK3C3 | |
| SCHEMBL6845074 | 0.77 | PIK3C3 (0.49) | PIP5K1CPIK3CAMAPK14PIK3C3 | |
| SCHEMBL626764 | 0.77 | MAPK14 (0.44) | PIP5K1CPIK3CAMAPK14PIK3C3 | |
| SCHEMBL6842871 | 0.77 | PIK3C3 (0.48) | PIP5K1CPIK3CAMAPK14PIK3C3 | |
| SCHEMBL6842841 | 0.75 | PIK3C3 (0.47) | MAPK14PIK3C3MAPK13MAPK12MAPK11 | |
| SCHEMBL6845017 | 0.75 | MAPK14 (0.49) | PIP5K1CPIK3CAMAPK14PIK3C3MAPK8 | |
| SCHEMBL6842853 | 0.75 | MAPK14 (0.61) | MAPK14PIK3C3MAPK8MAPK9IKBKB | |
| SCHEMBL6842872 | 0.75 | MAPK14 (0.45) | PIP5K1CPIK3CAMAPK14PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153300-A | Heteroaryls and uses thereof | MILLENNIUM PHARM INC | 2013-06-12 | — | — | CN | disclosed |