SCHEMBL27906375

SCHEMBL27906375

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nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.43
GRM8 O00222 1/20 0.43
GRM6 O15303 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GSR P00390 1/20 0.43
GRIK1 P39086 1/20 0.43
GRM5 P41594 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIK2 Q13002 1/20 0.43
GRIK3 Q13003 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5161294 1.00 CYP1A2 (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL6274477 1.00 CYP1A2 (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL2248721 0.90 CYP1A2 (0.50) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28486150 0.89 GRM8 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28486157 0.89 GRM8 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28464434 0.86 GRM8 (0.44) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28475140 0.82 GRM8 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28475131 0.82 GRM8 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL28666295 0.81 CYP1A2 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B
SCHEMBL10523165 0.81 CYP1A2 (0.52) CYP1A2GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118130682-A High-sensitivity analysis method for selectively enriching important biomarkers of brain tissue 上海交通大学 2024-06-04 CN disclosed
CN-111432844-B PSMA-targeting amanitine conjugates 海德堡医药研究有限责任公司 2023-10-27 CN disclosed
CN-116508787-A Urtica thunbergii leaf extract and preparation method and application thereof 贵州农业职业学院 2023-08-01 CN disclosed
CN-102272100-B Technetium-and rhenium-bis (heteroaryl) complexes for inhibition of PSMA and methods of use thereof 分子制药洞察公司 2016-08-17 CN disclosed
CN-102864196-B Method for preparing alpha-aspartyl small peptide by dihydroorotic acid enzyme method NANJING UNIVERSITY OF TECHNOLOGY 2014-07-02 CN disclosed
CN-103038252-A Improved complement receptor 2(CR2) targeting populations UNIV COLORADO A BODYCORPORATE 2013-04-10 CN disclosed
CN-102864196-A Method for preparing alpha-aspartyl small peptide by dihydroorotic acid enzyme method NANJING UNIVERSITY OF TECHNOLOGY 2013-01-09 CN disclosed
CN-102272100-A Technetium-and rhenium-bis (heteroaryl) complexes for inhibition of PSMA and methods of use thereof 2011-12-07 CN disclosed