Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575188 | 0.89 | CXCR2 (0.58) | CXCR2PPARACXCR1CA1CA2 | |
| SCHEMBL27907156 | 0.82 | CXCR2 (0.50) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL1820489 | 0.82 | CXCR2 (0.48) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL1821730 | 0.81 | CXCR2 (0.48) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL13313607 | 0.80 | CXCR2 (0.47) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL1820423 | 0.78 | CXCR2 (0.41) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL28831379 | 0.77 | CA1 (0.58) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL3584598 | 0.77 | CXCR2 (0.47) | CXCR2CXCR1CA1CA2CA9 | |
| SCHEMBL27925069 | 0.76 | MEN1 (0.49) | MEN1MAPTKMT2A | |
| SCHEMBL28797392 | 0.75 | CXCR2 (0.49) | CXCR2CXCR1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159674-A | 2-benzene alkyl amid compound and preparation method, medical composition and use thereof | SUZHOU ANNUO BIOLOG MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | claimed |
| CN-103159674-A | 2-benzene alkyl amid compound and preparation method, medical composition and use thereof | SUZHOU ANNUO BIOLOG MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | disclosed |