Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 4/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084 | 0.79 | HDAC1 (0.45) | LPAR1LPAR3ALDH1A1KDM4EGAA | |
| SCHEMBL15557712 | 0.79 | PTGS1 (0.50) | CXCR1CXCR2MMP1MMP2MMP9 | |
| SCHEMBL15547452 | 0.78 | CXCR1 (0.47) | CXCR1CXCR2MMP1MMP2MMP9 | |
| SCHEMBL3678803 | 0.77 | LPAR1 (0.53) | LPAR1LPAR3THRBALDH1A1GAA | |
| Reparixin SCHEMBL1884299 | 0.72 | CXCR2 (1.00) | CXCR1CXCR2THRBCHRM1PDE4A | |
| Reparixin SCHEMBL1884300 | 0.72 | CXCR2 (1.00) | CXCR1CXCR2THRBCHRM1PDE4A | |
| SCHEMBL27925089 | 0.71 | CXCR2 (0.54) | CXCR1CXCR2LPAR1LPAR3THRB | |
| SCHEMBL5091 | 0.71 | CA1 (0.45) | LPAR1LPAR3 | |
| SCHEMBL27907159 | 0.70 | CXCR1 (0.57) | CXCR1CXCR2THRBSCN9AALDH1A1 | |
| SCHEMBL27925055 | 0.70 | CXCR1 (0.74) | CXCR1CXCR2THRBCHRM1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159674-A | 2-benzene alkyl amid compound and preparation method, medical composition and use thereof | SUZHOU ANNUO BIOLOG MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | claimed |
| CN-103159674-A | 2-benzene alkyl amid compound and preparation method, medical composition and use thereof | SUZHOU ANNUO BIOLOG MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | disclosed |