Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540590 | 0.83 | HIF1A (0.56) | HIF1AALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL6266515 | 0.81 | AURKA (0.62) | HIF1AALDH1A1MAPTHTTGAA | |
| SCHEMBL7568812 | 0.81 | MAPK8 (0.60) | HIF1AALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL27907603 | 0.79 | ABCB1 (0.54) | HIF1AALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL27925715 | 0.78 | MAPT (0.66) | ALDH1A1MAPTL3MBTL1GAALMNA | |
| SCHEMBL27907664 | 0.78 | ABCB1 (0.68) | HIF1AALDH1A1MAPTHTTLMNA | |
| SCHEMBL805159 | 0.78 | HSD17B10 (0.65) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6483561 | 0.75 | HDAC8 (0.55) | HIF1AALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL8397299 | 0.74 | MAPT (0.50) | ALDH1A1MAPTHTTL3MBTL1GAA | |
| SCHEMBL3409860 | 0.74 | GAA (0.70) | HIF1AALDH1A1MAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140211-B | Skin care compositions comprising substituted monoamines | UNILEVER PLC | 2015-05-27 | — | — | CN | disclosed |
| CN-103140211-A | Skin care compositions comprising substituted monoamines | UNILEVER PLC | 2013-06-05 | — | — | CN | disclosed |