⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8388110 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL2430803 | 0.76 | — | — | |
| SCHEMBL899456 | 0.72 | — | — | |
| SCHEMBL21208 | 0.72 | — | — | |
| SCHEMBL3250426 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL28679898 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL27775807 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL169584 | 0.71 | — | — | |
| SCHEMBL10076721 | 0.69 | — | — | |
| SCHEMBL20071 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947319-B | Method and tertiary phosphine for phosphine oxides is reduced into corresponding tertiary phosphine in the presence of a catalyst is used for reducing in the presence of a catalyst the purposes of phosphine oxides | 克罗马福拉公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-102947319-A | A process for the reduction of a tertiary phosphine oxide to the corresponding tertiary phosphine in the presence of a catalyst and use of a tertiary phosphine for reducing a tertiary phosphine oxide in the presence of a catalyst | CHROMAFORA AB | 2013-02-27 | — | — | CN | disclosed |