Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28016859 | 0.86 | MAPK1 (0.56) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19905393 | 0.86 | MAPK1 (0.60) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9448273 | 0.83 | MAPK1 (0.66) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13451040 | 0.82 | MAPK1 (0.59) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16533219 | 0.81 | MAPK1 (0.58) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27909012 | 0.79 | PARP1 (0.42) | MAPK1TSHRCYP1A2KMT2APARP1 | |
| SCHEMBL10130619 | 0.78 | MAPK1 (0.55) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4249981 | 0.77 | MAPK1 (0.55) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL335681 | 0.77 | MAPK1 (0.77) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29415167 | 0.77 | MAPK1 (0.77) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189373-B | The Triazolopyridine replaced | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-06 | — | — | CN | disclosed |
| CN-103189373-A | Substituted triazolopyridines | BAYER IP GMBH | 2013-07-03 | — | — | CN | disclosed |