Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909539 | 0.98 | PARP1 (0.86) | PARP1 | |
| SCHEMBL5125432 | 0.91 | PARP1 (1.00) | PARP1 | |
| SCHEMBL15204327 | 0.89 | PARP1 (0.82) | PARP1 | |
| SCHEMBL27909427 | 0.88 | PARP1 (0.83) | PARP1 | |
| SCHEMBL27892344 | 0.88 | PARP1 (0.84) | PARP1 | |
| SCHEMBL5131324 | 0.86 | PARP1 (1.00) | PARP1 | |
| SCHEMBL15204588 | 0.86 | PARP1 (0.86) | PARP1 | |
| SCHEMBL27892319 | 0.86 | PARP1 (0.86) | PARP1 | |
| SCHEMBL27909307 | 0.86 | PARP1 (0.87) | PARP1 | |
| SCHEMBL5121608 | 0.86 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952118-B | Poly-(ADP-ribose) AG14361, preparation method and its usage | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-102952118-A | Poly(ADP-ribose)polymerase inhibitor, preparation method and application thereof | SHANGHAI DINUO MEDICAL TECHNOLOGY CO LTD | 2013-03-06 | — | — | CN | disclosed |