Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.79 |
| ▸ | CTSS | P25774 | 3/20 | 0.70 |
| ▸ | CTSK | P43235 | 2/20 | 0.70 |
| ▸ | CTSL | P07711 | 1/20 | 0.70 |
| ▸ | CTSB | P07858 | 1/20 | 0.70 |
| ▸ | PPARA | Q07869 | 5/20 | 0.64 |
| ▸ | PPARG | P37231 | 4/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606309 | 1.00 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL795685 | 1.00 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL21473784 | 1.00 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL67020 | 1.00 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL66220 | 1.00 | ACE (0.79) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL29707278 | 0.98 | ACE (0.77) | ACECTSSCTSKCTSLCTSB | |
| Water SCHEMBL15362012 | 0.98 | ACE (0.77) | ACECTSSCTSKCTSLCTSB | |
| Water SCHEMBL15362013 | 0.98 | ACE (0.77) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL26654474 | 0.98 | ACE (0.77) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL26654472 | 0.98 | ACE (0.77) | ACECTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105412092-B | Ester prodrugs of [3- (1- (1H-imidazol-4-yl) ethyl) -2-methylphenyl ] methanol for lowering intraocular pressure | 阿勒根公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-103221045-A | Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating skin diseases and conditions | ALLERGAN INC | 2013-07-24 | — | — | CN | disclosed |
| CN-103200942-A | Ester prodrugs of [3- (1- (1H-imidazol-4-yl) ethyl) -2-methylphenyl ] methanol | ALLERGAN INC | 2013-07-10 | — | — | CN | disclosed |
| CN-103200941-A | Ester prodrugs of [3- (1- (1H-imidazol-4-yl) ethyl) -2-methylphenyl ] methanol for lowering intraocular pressure | ALLERGAN INC | 2013-07-10 | — | — | CN | disclosed |