Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968725 | 0.84 | NR4A2 (0.64) | NR4A2CREBBPHSD17B10MAPTALOX15 | |
| SCHEMBL3918274 | 0.83 | NR4A2 (0.56) | NR4A2ARCREBBPCYP1A2MEN1 | |
| SCHEMBL28046327 | 0.80 | NR4A2 (0.49) | NR4A2CREBBP | |
| SCHEMBL3995062 | 0.80 | NR4A2 (0.72) | NR4A2CREBBP | |
| SCHEMBL5592328 | 0.80 | NR4A2 (0.49) | NR4A2CREBBPMEN1KMT2A | |
| SCHEMBL1759590 | 0.78 | NR4A2 (0.47) | NR4A2CREBBPMEN1MAPTKMT2A | |
| SCHEMBL1760252 | 0.78 | NR4A2 (0.47) | NR4A2CREBBPMEN1MAPTKMT2A | |
| SCHEMBL27771709 | 0.77 | NR4A2 (0.49) | NR4A2CREBBPMEN1MAPTKMT2A | |
| SCHEMBL28284795 | 0.77 | NR4A2 (0.49) | NR4A2ARCREBBPMEN1MAPT | |
| SCHEMBL9077031 | 0.76 | KMT2A (0.52) | HSD17B10MEN1MAPTKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145711-A | Azaadamantane ester and carbamate derivatives and methods of use thereof | ABBOTT LAB | 2013-06-12 | — | — | CN | disclosed |