Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27909705 | 1.00 | GAA (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL27909710 | 0.87 | CA12 (0.47) | GAAMGAMSIMGAM2BIRC2 | |
| SCHEMBL27909709 | 0.87 | CA12 (0.47) | GAAMGAMSIMGAM2BIRC2 | |
| SCHEMBL15359461 | 0.81 | CA12 (0.48) | GAABIRC2MAPTHSD17B10CA12 | |
| SCHEMBL15359456 | 0.81 | CA12 (0.48) | GAABIRC2MAPTHSD17B10CA12 | |
| SCHEMBL15055494 | 0.81 | CA12 (0.48) | GAABIRC2MAPTHSD17B10CA12 | |
| SCHEMBL18686187 | 0.79 | CA12 (0.47) | GAABIRC2MAPTHSD17B10CA12 | |
| SCHEMBL29845290 | 0.79 | CA12 (0.47) | GAAMGAMSIMGAM2BIRC2 | |
| SCHEMBL14902194 | 0.79 | CA12 (0.47) | GAAMGAMSIMGAM2BIRC2 | |
| SCHEMBL16587941 | 0.79 | CA12 (0.47) | GAABIRC2MAPTHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193669-B | nNOS-Capon uncoupling compound, preparation method and application thereof | NANJING MEDICAL UNIVERSITY (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-103193669-A | nNOS-Capon uncoupling compound, preparation method and application thereof | UNIV NANJING MEDICAL | 2013-07-10 | — | — | CN | disclosed |