Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47202 | 0.84 | — | — | |
| Urea SCHEMBL29094908 | 0.84 | NAPRT (0.38) | NAPRTMAPTKDM4EGAATSHR | |
| Hydrochloric Acid SCHEMBL27774929 | 0.82 | — | — | |
| SCHEMBL27859705 | 0.82 | — | — | |
| SCHEMBL27700371 | 0.82 | — | — | |
| Bromide SCHEMBL15820960 | 0.82 | — | — | |
| Hydrogen Sulfide SCHEMBL29094906 | 0.82 | — | — | |
| SCHEMBL28875380 | 0.82 | — | — | |
| SCHEMBL29278232 | 0.82 | — | — | |
| SCHEMBL27646532 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501074-A | Utilize acetylene acrylic acid | 北京华福工程有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-106715463-A | Glycated peptide compositions and uses thereof | 苏塞克斯研究实验室 | 2017-05-24 | — | — | CN | disclosed |
| CN-103209660-B | Cannula for expandable medical device | W.L.戈尔及同仁股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-103377836-A | Double electric layer capacitor electrolytic solution | OCEANS KING LIGHTING SCIENCE | 2013-10-30 | — | — | CN | disclosed |
| CN-103377834-A | Double electric layer capacitor electrolytic solution | OCEANS KING LIGHTING SCIENCE | 2013-10-30 | — | — | CN | disclosed |
| CN-102924739-A | High polymer material | WUXI ZHONGYI FILM TECHNOLOGY CO LTD | 2013-02-13 | — | — | CN | disclosed |