SCHEMBL27910552

SCHEMBL27910552

CCCCNC(=S)NC1CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
MEN1 O00255 1/20 1.00
LMNA P02545 1/20 0.66
ALDH1A1 P00352 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
PKM P14618 1/20 0.60
HTT P42858 1/20 0.56
EPHX1 P07099 9/20 0.56
EPHX2 P34913 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13684848 0.98 KMT2A (0.96) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL17956775 0.93 KMT2A (0.87) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL11596690 0.91 KMT2A (0.84) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL11595933 0.91 KMT2A (0.84) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL19420513 0.86 KMT2A (0.76) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL19420702 0.86 KMT2A (0.76) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL17956786 0.85 MEN1 (0.74) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL19420646 0.85 KMT2A (0.73) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL15224197 0.81 KMT2A (0.69) KMT2AMEN1LMNAALDH1A1CYP1A2
SCHEMBL23096787 0.81 KMT2A (0.68) KMT2AMEN1LMNAALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103204903-A Hepatitis c inhibitor compounds BOEHRINGER INGELHEIM INT 2013-07-17 CN disclosed