Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.68 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27928892 | 0.98 | HCRTR1 (0.66) | HCRTR1HCRTR2FAAHPDE10A | |
| SCHEMBL27911171 | 0.86 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL27911195 | 0.85 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL27911113 | 0.83 | HCRTR1 (0.63) | HCRTR1HCRTR2 | |
| SCHEMBL27928738 | 0.81 | HCRTR1 (0.66) | HCRTR1HCRTR2 | |
| SCHEMBL4538870 | 0.81 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27928879 | 0.81 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL4539774 | 0.80 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL27911333 | 0.79 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL27928885 | 0.79 | HCRTR1 (0.64) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201261-A | Lactam derivatives as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-07-10 | — | — | CN | disclosed |