Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929186 | 0.89 | CNR1 (0.53) | CNR1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12931831 | 0.83 | MEN1 (0.69) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL8323968 | 0.81 | CNR1 (0.70) | CNR1RAB9AKDM4ENPC1 | |
| SCHEMBL11803646 | 0.80 | EPHX1 (0.51) | CNR1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL15786287 | 0.80 | MEN1 (0.76) | MAPTMEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL21583073 | 0.78 | KDM4E (0.60) | CNR1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL11606641 | 0.78 | MAPT (0.58) | CNR1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL27929232 | 0.78 | KDM4E (0.54) | CNR1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL12930498 | 0.77 | MCHR1 (0.62) | CNR1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL23831486 | 0.77 | DHODH (0.65) | MAPTMEN1KMT2ARAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183682-B | C-10 carbamido substituted artemisinin derivative and preparation method and application thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-10-14 | — | — | CN | disclosed |
| CN-103183682-A | C-10 carbamido substituted artemisinin derivative and preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-07-03 | — | — | CN | disclosed |