Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 18/20 | 0.62 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023724 | 0.90 | MME (0.51) | MME | |
| SCHEMBL9938210 | 0.87 | MME (0.64) | MME | |
| SCHEMBL16458038 | 0.87 | MME (0.51) | MME | |
| SCHEMBL16458036 | 0.87 | MME (0.51) | MME | |
| SCHEMBL9935381 | 0.82 | MME (0.62) | MMEACE | |
| SCHEMBL9942293 | 0.82 | MME (0.62) | MMEACE | |
| SCHEMBL27913953 | 0.82 | MME (0.58) | MMEACR | |
| SCHEMBL27932205 | 0.82 | MME (0.60) | MME | |
| SCHEMBL27932191 | 0.81 | MME (0.45) | MME | |
| SCHEMBL27932188 | 0.81 | MME (0.60) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261168-B | Enkephalinase inhibitor | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-08-05 | — | — | CN | disclosed |
| CN-103261168-A | Enkephalinase inhibitors | THERAVANCE INC | 2013-08-21 | — | — | CN | disclosed |