Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436254 | 0.87 | HPGD (0.41) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL28493239 | 0.87 | HPGD (0.41) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL8003382 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL28249687 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL28098901 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL28442526 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL28843869 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL27910482 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| SCHEMBL27968431 | 0.84 | NPC1 (0.40) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29089406 | 0.83 | AURKA (0.39) | ALDH1A1SMN1; SMN2KDM4EHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103239718-B | Method for preparing adriamycin-loaded polycaprolactone-block-polyethylene glycol nano microspheres | UNIV JIANGSU | 2015-02-04 | — | — | CN | disclosed |
| CN-103239718-A | Method for preparing adriamycin-loaded polycaprolactone-block-polyethylene glycol nano microspheres | UNIV JIANGSU | 2013-08-14 | — | — | CN | disclosed |