SCHEMBL279148

SCHEMBL279148

COC(=O)C(N)C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
CA14 Q9ULX7 2/20 0.40
ALDH1A1 P00352 2/20 0.39
CA12 O43570 2/20 0.37
KMT2A Q03164 1/20 0.37
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
TSHR P16473 1/20 0.33
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL655143 0.97 SMN1; SMN2 (0.46) SMN1; SMN2CA14ALDH1A1CA12KMT2A
SCHEMBL10458392 0.87 SMN1; SMN2 (0.39) SMN1; SMN2CA14ALDH1A1CA12KMT2A
SCHEMBL2561278 0.85
SCHEMBL2930776 0.85
SCHEMBL27554292 0.85
SCHEMBL27833677 0.85
SCHEMBL24016832 0.84 GAA (0.44) SMN1; SMN2ALDH1A1KMT2ACA1CA2
Hydrochloric Acid SCHEMBL2840092 0.83 SMN1; SMN2 (0.40) SMN1; SMN2CA14ALDH1A1CA12KMT2A
SCHEMBL12216178 0.83
Hydrochloric Acid SCHEMBL5987780 0.83 SMN1; SMN2 (0.40) SMN1; SMN2CA14ALDH1A1CA12KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN claimed
CN-115304516-A Compounds with unconventional chromophores, their preparation and use 四川大学 2022-11-08 CN claimed
US-20260109840-A1 SOLID POLYELECTROLYTE COMPLEX-BASED PLASTICS FROM MODIFIED BIOPOLYMERS UNIV CHICAGO (US) 2026-04-23 US disclosed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 CN disclosed
CN-115304516-B Compounds with unconventional chromophores, their preparation and use 四川大学 2024-04-30 CN disclosed
CN-117843517-A Preparation method of impurity valeramide of imidazole aldehyde 云南云天化股份有限公司 2024-04-09 CN disclosed
CN-220159937-U Hydrogen chloride gas recycling and applying device in imidazole aldehyde continuous production 云南云天化股份有限公司 2023-12-12 CN disclosed
WO-2023107623-A2 BICYCLIC HETEROARENES AND METHODS OF THEIR USE Kineta, Inc. (US) 2023-06-15 WO disclosed
US-20230098076-A1 A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN (IN) 2023-03-30 US disclosed
US-11529760-B2 Polymeric materials and articles manufactured there from THE PROCTER & GAMBLE COMPANY (US) 2022-12-20 US disclosed
CN-113336667-B Method suitable for industrial production of intermediate of roxasistat 南京正济医药研究有限公司 2022-12-13 CN disclosed
EP-0275480-A2 Renin inhibitors IV WARNER-LAMBERT COMPANY (US) 1988-07-27 EP disclosed
US-4719288-A HYPOTENSIVE CIBA-GEIGY CORPORATION (US) 1988-01-12 US disclosed
US-4613676-A PEPTIDES CIBA-GEIGY CORPORATION (US) 1986-09-23 US disclosed
US-4595532-A N-(substituted-methyl)-azetidin-2-ones UNIVERSITY OF NOTRE DAME DU LAC (US) 1986-06-17 US disclosed
US-4510141-A (1,2,4) TRIAZOLO(1,5-A) QUINOXALINE OR PYRIDO(2,3-E)(U,2,4)TRIAZOLO(1,5-A)PYRAZINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1985-04-09 US disclosed
EP-0116432-A2 Improvements in or relating to N-(substituted-methyl)-azetidin-2-ones THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1984-08-22 EP disclosed
US-4130717-A Process and intermediates for isoindole derivatives HOFFMANN-LA ROCHE INC. (US) 1978-12-19 US disclosed
US-4089875-A Process and intermediates for isoindole derivatives HOFFMANN-LA ROCHE INC. (US) 1978-05-16 US disclosed
US-3966793-A ORTHO-AMINOARYL KETIMINES CLIN MIDY (FR) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230098076-A1 A PROCESS FOR PREPARATION OF 3,6-DICHLOROCYANO PYRAZINE, 3,6-DIOXOPIPERAZINE DERIVATIVES AND PRODUCTION OF FAVIPIRAVIR THEREOF CBR3, CYP4F3, CYP3A5 SMN1; SMN2 4197/4885CA14 1892/4885ALDH1A1 3833/4885
US-20260109840-A1 SOLID POLYELECTROLYTE COMPLEX-BASED PLASTICS FROM MODIFIED BIOPOLYMERS ALG1, PARN, LCP1 SMN1; SMN2 3151/4885CA14 380/4885ALDH1A1 2896/4885
US-11529760-B2 Polymeric materials and articles manufactured there from ALG3, CD68, VCL SMN1; SMN2 1266/4885CA14 1491/4885ALDH1A1 4802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.