Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL28062333 | 0.95 | PTGS1 (0.39) | PTGS1PTGS2 | |
| SCHEMBL321324 | 0.73 | PTGS1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL14739789 | 0.73 | PTGS1 (0.38) | PTGS1PTGS2 | |
| Boric Acid SCHEMBL29141876 | 0.70 | CA1 (0.41) | PTGS1PTGS2PPARA | |
| SCHEMBL20242720 | 0.70 | PTGS1 (0.47) | PTGS1PTGS2BACE1 | |
| SCHEMBL20242718 | 0.70 | PTGS1 (0.47) | PTGS1PTGS2BACE1 | |
| SCHEMBL28392420 | 0.69 | PTGS1 (0.45) | PTGS1PTGS2BACE1 | |
| SCHEMBL24204720 | 0.66 | PTGS1 (0.42) | PTGS1PTGS2BACE1PPARGPPARA | |
| SCHEMBL12495291 | 0.66 | PTGS1 (0.42) | PTGS1PTGS2BACE1 | |
| Boric Acid SCHEMBL29429197 | 0.65 | PTGS1 (0.39) | PTGS1PTGS2BACE1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068827-A | Fused heterocyclic derivatives as s1p modulators | ABBOTT HEALTHCARE PRODUCTS BV | 2013-04-24 | — | — | CN | disclosed |