Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26915960 | 0.85 | P2RX4 (0.40) | KMT2AP2RX4TYMPBLMGSK3A | |
| SCHEMBL26915968 | 0.84 | KMT2A (0.41) | KMT2AP2RX4TYMPBLMGSK3A | |
| SCHEMBL5798118 | 0.83 | NOTUM (0.44) | KMT2AP2RX4KDM4EALDH1A1 | |
| SCHEMBL26916740 | 0.83 | P2RX4 (0.41) | KMT2AP2RX4TYMPGSK3AGSK3B | |
| SCHEMBL26916098 | 0.82 | P2RX4 (0.38) | KMT2AP2RX4TYMPBLMGSK3A | |
| SCHEMBL26916087 | 0.82 | KMT2A (0.40) | KMT2AP2RX4TYMPGSK3AGSK3B | |
| SCHEMBL16632642 | 0.82 | KMT2A (0.46) | KMT2AP2RX4TYMPGSK3AGSK3B | |
| SCHEMBL26231008 | 0.81 | P2RX4 (0.35) | KMT2AP2RX4TYMPBLMGSK3A | |
| SCHEMBL7256423 | 0.81 | P2RX4 (0.39) | KMT2AP2RX4TYMPGSK3AGSK3B | |
| SCHEMBL7260294 | 0.81 | P2RX4 (0.39) | KMT2AP2RX4TYMPGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068834-A | Phosphoramidites for reverse RNA synthesis | CHEMGENES CORP | 2013-04-24 | — | — | CN | claimed |
| CN-103068834-A | Phosphoramidites for reverse RNA synthesis | CHEMGENES CORP | 2013-04-24 | — | — | CN | disclosed |