SCHEMBL27917554

SCHEMBL27917554

Oc1ccccc1-c1ccn[nH]1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.96
PIM1 P11309 1/20 0.55
NOTUM Q6P988 2/20 0.54
SCN4A P35499 2/20 0.52
HPGDS O60760 2/20 0.47
ALOX15 P16050 1/20 0.47
CCNB2 O95067 1/20 0.46
CDK1 P06493 1/20 0.46
CCNB1 P14635 1/20 0.46
GSK3A P49840 1/20 0.46
GSK3B P49841 1/20 0.46
CDK5 Q00535 1/20 0.46
CDK5R1 Q15078 1/20 0.46
CCNB3 Q8WWL7 1/20 0.46
RIPK1 Q13546 1/20 0.45
CASP6 P55212 1/20 0.43
NPC1 O15118 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
RAB9A P51151 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29998937 0.98 IDO1 (1.00) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL1501845 0.98 IDO1 (1.00) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL30763920 0.79 IDO1 (0.67) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL29176683 0.79 IDO1 (0.67) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL5536772 0.77 IDO1 (0.64) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL30837200 0.77 IDO1 (0.64) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL23923926 0.77 IDO1 (0.64) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL2339759 0.75 IDO1 (0.62) IDO1PIM1SCN4AHPGDSNPC1
SCHEMBL21324986 0.75 IDO1 (0.62) IDO1PIM1NOTUMSCN4AHPGDS
SCHEMBL29693625 0.75 IDO1 (0.62) IDO1PIM1SCN4AHPGDSNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104650047-A Substituted sodium 1H-pyrazol-5-olate BAYER IP GMBH 2015-05-27 CN disclosed
CN-103270031-A Substituted sodium 1H-pyrazole-5-olate BAYER IP GMBH 2013-08-28 CN disclosed