Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789767 | 0.93 | DPP4 (0.34) | BTKADRA1APROKR1ALDH1A1TSHR | |
| SCHEMBL2789770 | 0.93 | DPP4 (0.34) | BTKADRA1APROKR1ALDH1A1TSHR | |
| SCHEMBL2791634 | 0.93 | DPP4 (0.34) | BTKADRA1APROKR1ALDH1A1TSHR | |
| SCHEMBL2789049 | 0.93 | DPP4 (0.34) | BTKADRA1APROKR1ALDH1A1TSHR | |
| SCHEMBL2790275 | 0.88 | DPP4 (0.36) | BTKADRA1ACYP2D6DPP4DPP8 | |
| SCHEMBL2789275 | 0.86 | DPP4 (0.34) | BTKPROKR1ALDH1A1TSHRKMT2A | |
| SCHEMBL2789391 | 0.86 | DPP4 (0.34) | BTKPROKR1ALDH1A1TSHRKMT2A | |
| SCHEMBL2789278 | 0.86 | DPP4 (0.34) | BTKPROKR1ALDH1A1TSHRKMT2A | |
| SCHEMBL2787970 | 0.86 | DPP4 (0.34) | BTKPROKR1ALDH1A1TSHRKMT2A | |
| SCHEMBL2788040 | 0.85 | BTK (0.33) | BTKADRA1APROKR1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | claimed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |