SCHEMBL27920190

SCHEMBL27920190

Cc1cc(C(=O)O)ccc1-n1nc(C)c(Cl)c1C

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.65
POLB P06746 1/20 0.65
KMT2A Q03164 1/20 0.65
MYC P01106 2/20 0.51
ESR1 P03372 1/20 0.51
ALOX15 P16050 1/20 0.51
PTPN7 P35236 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 1/20 0.49
RARG P13631 1/20 0.48
RORC P51449 1/20 0.48
ENPP3 O14638 6/20 0.44
ALPL P05186 6/20 0.44
XIAP P98170 6/20 0.44
ENPP1 P22413 3/20 0.44
ELANE P08246 1/20 0.44
HTR7 P34969 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20502192 0.89 POLB (0.65) MEN1POLBKMT2AMYCESR1
SCHEMBL27938684 0.87 POLB (0.63) MEN1POLBKMT2AMYCESR1
SCHEMBL21935952 0.80 MEN1 (0.69) MEN1POLBKMT2AMYCALOX15
SCHEMBL15701753 0.80 POLB (0.54) MEN1POLBKMT2ALMNAL3MBTL1
SCHEMBL27920218 0.75 MYC (0.59) MEN1KMT2AMYCESR1ALOX15
SCHEMBL16761045 0.73 KMT2A (0.49) MEN1POLBKMT2AALOX15HSD17B10
SCHEMBL15442859 0.72 MYC (0.55) MEN1POLBKMT2AMYCESR1
SCHEMBL27613184 0.69 MYC (0.60) MEN1POLBKMT2AMYCESR1
SCHEMBL25765389 0.69 MEN1 (0.57) MEN1POLBKMT2ALMNAENPP3
SCHEMBL2115309 0.68 MYC (1.00) MEN1POLBKMT2AMYCESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339112-A Topical antifungal agent MEIJI SEIKA PHARMA CO LTD 2013-10-02 CN disclosed