Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006871 | 0.84 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL9884055 | 0.82 | CYP2C19 (0.67) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL218275 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL29366631 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17009420 | 0.81 | CYP2C19 (0.54) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL25948667 | 0.79 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL10547703 | 0.79 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL21685477 | 0.78 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL18040445 | 0.77 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 | |
| SCHEMBL17017087 | 0.77 | CYP2C19 (0.61) | NPC1RAB9ASMN1; SMN2CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103262854-A | Lycoris radiate herb bulb tillering promoter and application method thereof | UNIV CHANGSHA SCIENCE | 2013-08-28 | — | — | CN | disclosed |