Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Columbianetin SCHEMBL50251 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| Columbianetin SCHEMBL20356593 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| Columbianetin SCHEMBL21527679 | 0.81 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL30256774 | 0.76 | KDM4E (0.79) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL12247775 | 0.76 | KDM4E (0.79) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL31438609 | 0.76 | KDM4E (0.79) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL19313395 | 0.75 | DPP4 (0.59) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| Lomatin SCHEMBL6273711 | 0.72 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| (+)-Lomatin SCHEMBL29707947 | 0.72 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 | |
| Columbianadin SCHEMBL14424509 | 0.71 | KDM4E (1.00) | KDM4EHPGDALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103109820-A | Use of Columbianadin as agricultural insect antifeedant and pesticide | INST BOTANY JIANGSU PROVINCE & CAS | 2013-05-22 | — | — | CN | disclosed |