Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL11157270 | 0.86 | — | — | |
| Pyridine SCHEMBL3856560 | 0.67 | — | — | |
| Pyridine SCHEMBL27847499 | 0.67 | — | — | |
| Pyridine SCHEMBL27911910 | 0.67 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28253110 | 0.67 | TSHR (0.53) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL27519155 | 0.64 | — | — | |
| Pyridine SCHEMBL27519156 | 0.64 | TSHR (0.82) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL3118016 | 0.64 | — | — | |
| Benzene SCHEMBL10751789 | 0.64 | TSHR (1.00) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL16 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575045-A | Thienopyrimidines, preparation method, Pharmaceutical composition and its application | 南京红云生物科技有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-103140466-A | Process for preparing compound by novel sandmeyer-like reaction using nitroxide radical compound as reaction catalyst | DAIICHI SANKYO CO LTD | 2013-06-05 | — | — | CN | claimed |
| CN-109575045-A | Thienopyrimidines, preparation method, Pharmaceutical composition and its application | 南京红云生物科技有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-107698603-A | Thienopyrimidines, its preparation method, Pharmaceutical composition and its application | 厦门大学 | 2018-02-16 | — | — | CN | disclosed |
| CN-103140466-B | Compound oxygen radical of nitrogen is adopted to prepare the method for compound through the reaction of new sandmeyer type as catalysts | DAIICHI SANKYO Co.,Ltd. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103140466-A | Process for preparing compound by novel sandmeyer-like reaction using nitroxide radical compound as reaction catalyst | DAIICHI SANKYO CO LTD | 2013-06-05 | — | — | CN | disclosed |