Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 7/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27903920 | 0.90 | PTPN1 (0.40) | PTPN1PPARAPPARGALDH1A1 | |
| SCHEMBL27903918 | 0.88 | PTPN1 (0.33) | PTPN1PPARAPPARG | |
| SCHEMBL27903959 | 0.85 | PTPN1 (0.40) | PTPN1PPARAPPARG | |
| SCHEMBL27921854 | 0.83 | PTPN1 (0.36) | PTPN1PPARAPPARG | |
| SCHEMBL1699684 | 0.83 | CYP3A4 (0.45) | PPARAPPARGALDH1A1HTT | |
| SCHEMBL27921901 | 0.83 | GCGR (0.40) | PTPN1PPARAPPARG | |
| SCHEMBL27903929 | 0.83 | PTPN1 (0.38) | PTPN1PPARAPPARG | |
| SCHEMBL27922056 | 0.82 | PTPN1 (0.38) | PTPN1PPARAPPARG | |
| SCHEMBL27903953 | 0.82 | CYP3A4 (0.39) | PTPN1 | |
| SCHEMBL27903904 | 0.80 | PTPN1 (0.38) | PTPN1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103140474-A | Naphthalen-2-ylacetic acid derivatives for the treatment of AIDS | GILEAD SCIENCES INC | 2013-06-05 | — | — | CN | disclosed |