Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923642 | 1.00 | GFER (0.58) | GFERS1PR1MAPTLMNAMEN1 | |
| SCHEMBL1371962 | 0.96 | S1PR1 (0.56) | GFERS1PR1MAPTLMNAMEN1 | |
| SCHEMBL1371965 | 0.96 | S1PR1 (0.56) | GFERS1PR1MAPTLMNAMEN1 | |
| SCHEMBL1373143 | 0.90 | MEN1 (0.61) | GFERS1PR1MAPTLMNAMEN1 | |
| SCHEMBL1373140 | 0.90 | MEN1 (0.61) | GFERS1PR1MAPTLMNAMEN1 | |
| SCHEMBL1372466 | 0.89 | S1PR1 (0.60) | S1PR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1372470 | 0.89 | S1PR1 (0.60) | S1PR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1373826 | 0.87 | S1PR1 (0.60) | S1PR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1373823 | 0.87 | S1PR1 (0.60) | S1PR1MAPTLMNAMEN1KMT2A | |
| SCHEMBL1371771 | 0.85 | S1PR1 (0.56) | S1PR1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245174-B | Synergistic effects between sphingosine-1-phosphate receptor antagonists and antimicrotubule agents | EXELIXIS INC | 2013-11-06 | — | — | CN | disclosed |