Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942795 | 0.93 | S1PR1 (0.56) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL9107811 | 0.91 | S1PR1 (0.53) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL27942984 | 0.91 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL28808364 | 0.90 | S1PR1 (0.60) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL27923772 | 0.90 | S1PR5 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL27942799 | 0.85 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL27923768 | 0.85 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL9105697 | 0.84 | S1PR1 (0.55) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL9106954 | 0.83 | S1PR1 (0.57) | S1PR1S1PR5S1PR4S1PR3 | |
| SCHEMBL27923774 | 0.83 | S1PR1 (0.54) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370065-A | Novel benzyl azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators | ALLERGAN INC | 2013-10-23 | — | — | CN | claimed |
| CN-103370065-A | Novel benzyl azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators | ALLERGAN INC | 2013-10-23 | — | — | CN | disclosed |