Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 8/20 | 0.52 |
| ▸ | CA1 | P00915 | 7/20 | 0.52 |
| ▸ | CA9 | Q16790 | 7/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzonitrile SCHEMBL28806619 | 0.85 | TSHR (0.70) | TSHRNPC1MTORRAB9ACA2 | |
| Benzonitrile SCHEMBL7635221 | 0.85 | TSHR (0.70) | TSHRNPC1MTORRAB9ACA2 | |
| Benzonitrile SCHEMBL12469615 | 0.85 | TSHR (0.70) | TSHRNPC1MTORRAB9ACA2 | |
| Benzonitrile SCHEMBL65862 | 0.85 | TSHR (0.70) | TSHRNPC1MTORRAB9ACA2 | |
| Benzonitrile SCHEMBL29059725 | 0.84 | TSHR (0.88) | TSHRCA2CA1CA9CA12 | |
| Benzonitrile SCHEMBL22444750 | 0.84 | TSHR (0.88) | TSHRCA2CA9CA12MAPT | |
| Benzonitrile SCHEMBL9464940 | 0.84 | TSHR (1.00) | TSHRCA2CA9CA12MAPT | |
| Benzonitrile SCHEMBL11044747 | 0.84 | — | — | |
| Benzonitrile SCHEMBL30929383 | 0.84 | TSHR (1.00) | TSHRCA2CA9CA12MAPT | |
| Benzonitrile SCHEMBL6640 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-103153096-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 赛诺米克斯公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | disclosed |