SCHEMBL27923932

SCHEMBL27923932

Cc1nc2cccc(OC3CCCCC3)c2c(N)c1C(=O)O.[NaH]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 2/20 0.42
TP53 P04637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PDGFRB P09619 1/20 0.38
FGFR1 P11362 1/20 0.38
KDR P35968 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
PDE4A P27815 3/20 0.37
PDE4B Q07343 3/20 0.37
PDE4C Q08493 3/20 0.37
PDE4D Q08499 3/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358378 0.99 MCHR1 (0.43) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL620347 0.99 MCHR1 (0.43) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL621608 0.99 MCHR1 (0.43) MCHR1TP53HSD17B10PDGFRBFGFR1
Hydrochloric Acid SCHEMBL618260 0.98 MCHR1 (0.42) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL620752 0.98 HSD17B10 (0.41) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL17730198 0.89 MCHR1 (0.46) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL17730242 0.89 HSD17B10 (0.40) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL17730243 0.89 HSD17B10 (0.40) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL21281167 0.89 MCHR1 (0.46) MCHR1TP53HSD17B10PDGFRBFGFR1
SCHEMBL17740882 0.89 KMT2A (0.40) MCHR1TP53HSD17B10PDGFRBFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106107406-B Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers 弗门尼舍公司 2020-06-09 CN disclosed
CN-106107406-A Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers 赛诺米克斯公司 2016-11-16 CN disclosed
CN-103153096-B Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers 赛诺米克斯公司 2016-08-03 CN disclosed
CN-103153096-A Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers SENOMYX INC 2013-06-12 CN disclosed