Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907338 | 0.96 | MELK (0.80) | MELK | |
| SCHEMBL10281883 | 0.89 | MELK (1.00) | MELK | |
| SCHEMBL530034 | 0.89 | MELK (1.00) | MELK | |
| SCHEMBL530416 | 0.89 | MELK (1.00) | MELK | |
| SCHEMBL530035 | 0.89 | MELK (1.00) | MELK | |
| SCHEMBL28803896 | 0.87 | MELK (0.79) | MELK | |
| SCHEMBL530263 | 0.85 | MELK (1.00) | MELK | |
| SCHEMBL530009 | 0.84 | MELK (1.00) | MELK | |
| SCHEMBL530144 | 0.83 | MELK (0.81) | MELK | |
| SCHEMBL530234 | 0.83 | MELK (1.00) | MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153063-A | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-06-12 | — | — | CN | disclosed |