Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 19/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907479 | 0.91 | PDE5A (0.61) | PDE5A | |
| SCHEMBL27907471 | 0.88 | PDE5A (0.54) | PDE5A | |
| SCHEMBL27907474 | 0.84 | PDE5A (0.60) | PDE5A | |
| SCHEMBL27925563 | 0.84 | PDE5A (0.58) | PDE5A | |
| SCHEMBL327115 | 0.83 | PDE5A (0.66) | PDE5A | |
| SCHEMBL326635 | 0.79 | PDE5A (0.62) | PDE5A | |
| SCHEMBL27907468 | 0.79 | PDE5A (0.65) | PDE5A | |
| SCHEMBL27925558 | 0.79 | PDE5A (0.61) | PDE5A | |
| SCHEMBL27979435 | 0.77 | PDE5A (0.60) | PDE5A | |
| SCHEMBL27907475 | 0.77 | PDE5A (0.60) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097387-B | Ring-fused pyrimidines and triazines and use thereof for treating and/or preventing cardiovascular diseases | 拜耳知识产权有限责任公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-103097387-A | Ring-fused pyrimidines and triazines and use thereof for treating and/or preventing cardiovascular diseases | BAYER IP GMBH | 2013-05-08 | — | — | CN | disclosed |