Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12956573 | 0.93 | IAPP (0.49) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8186371 | 0.86 | NPSR1 (0.47) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31689801 | 0.86 | NPSR1 (0.68) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL324789 | 0.86 | NPSR1 (0.68) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12226963 | 0.85 | NPSR1 (0.46) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27696939 | 0.82 | POLB (0.47) | IAPP | |
| SCHEMBL27802926 | 0.82 | NPSR1 (0.47) | NPSR1 | |
| SCHEMBL6498578 | 0.82 | KMT2A (0.46) | NPSR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27643611 | 0.81 | NPSR1 (0.46) | NPSR1TP53L3MBTL1ALDH1A1HDAC3 | |
| SCHEMBL1454248 | 0.81 | TSHR (0.56) | NPSR1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611005-B | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA AS | 2013-11-06 | — | — | CN | disclosed |