SCHEMBL27929338

SCHEMBL27929338

c1ccc(CCCNC2CCCCC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 11/20 0.71
SIGMAR1 Q99720 4/20 0.71
GRIN1 Q05586 2/20 0.71
TAAR1 Q96RJ0 1/20 0.69
EPHX1 P07099 2/20 0.61
KMT2A Q03164 1/20 0.61
CXCR4 P61073 2/20 0.58
OPRM1 P35372 1/20 0.57
OPRL1 P41146 1/20 0.57
EPHX2 P34913 1/20 0.56
CXCL12 P48061 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9396249 0.98 GRIN2B (0.69) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL23019750 0.93 GRIN2B (0.69) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL21242573 0.93 GRIN2B (0.69) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL23599404 0.93 GRIN2B (0.69) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL9263068 0.91 CXCR4 (0.66) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL24767088 0.89 TAAR1 (0.84) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL22216853 0.89 TAAR1 (0.84) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL25002632 0.89 TAAR1 (0.84) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL21792273 0.89 TAAR1 (0.84) GRIN2BSIGMAR1GRIN1TAAR1EPHX1
SCHEMBL24075499 0.89 TAAR1 (0.84) GRIN2BSIGMAR1GRIN1TAAR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435430-B Method for reducing amide compounds UNIV SICHUAN 2015-02-18 CN disclosed
CN-103435430-A Method for reducing amide compounds UNIV SICHUAN 2013-12-11 CN disclosed