Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590595 | 0.88 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2595775 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL17679891 | 0.81 | PDE10A (0.83) | PDE10A | |
| SCHEMBL2596138 | 0.76 | PDE10A (0.77) | PDE10A | |
| SCHEMBL2595751 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596333 | 0.74 | PDE10A (0.81) | PDE10A | |
| SCHEMBL2595767 | 0.73 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596310 | 0.73 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596345 | 0.73 | PDE10A (0.71) | PDE10A | |
| SCHEMBL2595741 | 0.72 | PDE10A (0.76) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221404-A | Nitrogen heterocyclic compounds useful as PDE10 inhibitors | AMGEN INC | 2013-07-24 | — | — | CN | claimed |