SCHEMBL27934827

SCHEMBL27934827

c1ccc2c(c1)Cc1c-2ccc2c1ccc1c3ccccc3ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.50
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 2/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
PNMT P11086 1/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP1A2 P05177 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31199126 1.00 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL2486633 1.00 HPRT1 (0.50) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL150250 0.91 CA1 (0.46) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL29432662 0.91 CA1 (0.46) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL29620372 0.91 CA1 (0.46) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL29413802 0.91 CA1 (0.46) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL27981434 0.89 CA1 (0.44) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL22645278 0.88 CA1 (0.39) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL27934806 0.88 HPRT1 (0.39) HPRT1ALDH1A1HSD17B10CYP2A6TSHR
Benzo(A)Fluorene SCHEMBL27835930 0.87 CA1 (0.38) HPRT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103539737-A Aza-phenanthro-fluorene derivative and preparation method thereof as well as electrically-induced fluorescence luminescent device TCL GROUP CO LTD 2014-01-29 CN disclosed