Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.32 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.32 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305126 | 0.92 | TNKS (0.34) | AURKAAURKBINCENPTPX2CCNT1 | |
| SCHEMBL27935533 | 0.89 | CHEK1 (0.34) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL27950054 | 0.88 | PTGDR2 (0.33) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL27935529 | 0.88 | CCNT1 (0.39) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL27950080 | 0.86 | TNIK (0.37) | PIK3CAMTOR | |
| SCHEMBL27935539 | 0.82 | PIK3CA (0.35) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL27935531 | 0.80 | CHEK1 (0.37) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL303796 | 0.80 | PTGDR2 (0.36) | — | |
| SCHEMBL27935511 | 0.80 | PTGDR2 (0.36) | CHEK1AURKARPS6KA5RPS6KA4KIT | |
| SCHEMBL1922092 | 0.79 | SMO (0.42) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203067-B | Hedgehog pathway modulators | IRM LLC | 2014-01-15 | — | — | CN | claimed |