Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL27938005

CCCCc1cc(C)cc2ccccc12.N

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
CYP2A6 P11509 1/20 0.48
TLR8 Q9NR97 2/20 0.44
MAPT P10636 1/20 0.41
LMNA P02545 2/20 0.39
ABCB11 O95342 1/20 0.39
CYP2D6 P10635 1/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SCN3A Q9NY46 1/20 0.39
NOS2 P35228 1/20 0.38
ADORA3 P0DMS8 2/20 0.37
NCEH1 Q6PIU2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADORA1 P30542 1/20 0.37
BCHE P06276 1/20 0.36
TLR7 Q9NYK1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27919173 0.93 MAPT (0.49) CYP1A2CYP2A6TLR8MAPTTDP1
Ammonia Solution, Strong SCHEMBL27919149 0.93 MAPT (0.49) CYP1A2CYP2A6TLR8MAPTTDP1
SCHEMBL27471657 0.93 CYP1A2 (0.48) CYP1A2CYP2A6TLR8MAPTTDP1
SCHEMBL5833000 0.87 CYP1A2 (0.53) CYP1A2CYP2A6MAPTCYP2D6TDP1
SCHEMBL27477260 0.85 CYP1A2 (0.59) CYP1A2CYP2A6CYP2D6TDP1ALDH1A1
SCHEMBL7654443 0.83 CYP1A2 (0.48) CYP1A2CYP2A6CYP2D6TDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL28805674 0.82 CYP1A2 (0.55) CYP1A2CYP2A6MAPTCYP2D6TDP1
Ammonia Solution, Strong SCHEMBL27937854 0.81 CYP1A2 (0.50) CYP1A2CYP2A6TLR8MAPTTDP1
SCHEMBL7655964 0.81 CYP1A2 (0.47) CYP1A2CYP2A6TLR8MAPTCYP2D6
SCHEMBL27279895 0.81 TLR8 (0.45) CYP1A2TLR8MAPTLMNAABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103298772-B Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2015-06-24 CN disclosed
CN-103298772-A Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2013-09-11 CN disclosed