Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17763937 | 0.82 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL17763851 | 0.81 | CNR2 (0.72) | CNR2CNR1 | |
| SCHEMBL17763930 | 0.81 | CNR2 (0.74) | CNR2CNR1 | |
| SCHEMBL14152486 | 0.79 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL14151449 | 0.79 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL14226272 | 0.73 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL28031716 | 0.72 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL28809495 | 0.71 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL27938623 | 0.71 | CNR2 (0.35) | CNR2CNR1LRRK2 | |
| SCHEMBL28031676 | 0.71 | CNR2 (0.53) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608332-A | Pyridine-2-amides useful as CB2 agonists | HOFFMANN LA ROCHE | 2014-02-26 | — | — | CN | disclosed |