Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 18/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808799 | 0.92 | FLT3 (0.73) | FLT3 | |
| SCHEMBL12272799 | 0.86 | FLT3 (0.73) | FLT3 | |
| SCHEMBL12271794 | 0.86 | FLT3 (1.00) | FLT3 | |
| SCHEMBL12272488 | 0.85 | FLT3 (0.72) | FLT3 | |
| SCHEMBL12272358 | 0.85 | FLT3 (1.00) | FLT3 | |
| SCHEMBL27945696 | 0.83 | FLT3 (0.85) | FLT3 | |
| SCHEMBL12526970 | 0.78 | FLT3 (0.84) | FLT3 | |
| SCHEMBL12272060 | 0.78 | FLT3 (0.71) | FLT3 | |
| SCHEMBL12273104 | 0.77 | FLT3 (0.73) | FLT3 | |
| SCHEMBL12272379 | 0.76 | FLT3 (1.00) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429593-A | Imidazo pyrazines | HOFFMANN LA ROCHE | 2013-12-04 | — | — | CN | disclosed |